![]() Microtubules that will form the mitotic spindle extend between the centrosomes, pushing them farther apart as the microtubule fibers lengthen. The centrosomes begin to move to opposite poles of the cell. The nucleus reforms and the cell divides.ĭuring prophase, the “first phase,” the nuclear envelope starts to dissociate into small vesicles, and the membranous organelles (such as the Golgi complex or Golgi apparatus, and endoplasmic reticulum), fragment and disperse toward the periphery of the cell. Chromosome condensation can be visualized by the various stains during the prophase. During the prophase, chromatin condenses, and nucleolus disappears. ![]() Prophase begins after a G2 phase of the interphase. Prophase runs for a short period of time. Cohesin proteins break down and the sister chromatids separate. Prophase is the first phase of mitotic phase of the cell cycle. ![]() Sister chromatids line up at the metaphase plate. The kinetochore becomes attached to the mitotic spindle.The nucleus reforms and the cell divides. The kinetochore breaks down and the sister chromatids separate. The kinetochore becomes attached to the cohesin proteins.Cohesin proteins break down and the sister chromatids separate. The kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate.Which of the following is the correct order of events in mitosis? (credit “mitosis drawings”: modification of work by Mariana Ruiz Villareal credit “micrographs”: modification of work by Roy van Heesbeen credit “cytokinesis micrograph”: Wadsworth Center/New York State Department of Health scale-bar data from Matt Russell) The pictures at the bottom were taken by fluorescence microscopy (hence, the black background) of cells artificially stained by fluorescent dyes: blue fluorescence indicates DNA (chromosomes) and green fluorescence indicates microtubules (spindle apparatus). Karyokinesis (or mitosis) is divided into five stages-prophase, prometaphase, metaphase, anaphase, and telophase. The Importance of Biodiversity to Human Life Human Reproductive Anatomy and Gametogenesisįertilization and Early Embryonic DevelopmentĬlimate and the Effects of Global Climate ChangeĮnvironmental Limits to Population Growthīehavioral Biology: Proximate and Ultimate Causes of Behavior Hormonal Control of Osmoregulatory Functions Transport of Gases in Human Bodily Fluids The Evolutionary History of the Animal KingdomĪnimal Nutrition and the Digestive System Other Acellular Entities: Prions and Viroids Prevention and Treatment of Viral Infections Viral Evolution, Morphology, and Classification Mendel’s Experiments and the Laws of ProbabilityĮukaryotic Post-transcriptional Gene RegulationĮukaryotic Translational and Post-translational Gene Regulation Signaling Molecules and Cellular Receptors Using Light Energy to Make Organic Molecules The Light-Dependent Reactions of Photosynthesis Oxidation of Pyruvate and the Citric Acid CycleĬonnections of Carbohydrate, Protein, and Lipid Metabolic Pathways Potential, Kinetic, Free, and Activation Energy Structure and Function of Plasma Membranes Atoms, Isotopes, Ions, and Molecules: The Building BlocksĬonnections between Cells and Cellular Activities
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